You can use Site Recovery Manager protection and VMware Cloud Disaster Recovery high-frequency snapshots on the same virtual machine, with certain limitations.
You can replicate a VMware Cloud Disaster Recovery high-frequency snapshot protected virtual machine with vSphere Replication and include the virtual machine in a vSphere Replication protection group.
If you have a virtual machine that is already replicated by vSphere Replication and added in a Site Recovery Manager protection group, you cannot protect this VM with VMware Cloud Disaster Recovery. The VMware Cloud Disaster Recovery protection fails with the following error: "Another vendor has already initiated an operation on the protected entity."
You cannot perform a parallel failover of the same VM with VMware Cloud Disaster Recovery and Site Recovery Manager.
You cannot include a VMware Cloud Disaster Recovery high-frequency snapshot protected virtual machine in an array-based replication protection group or a Virtual Volumes protection group.