You can use Site Recovery Manager when protecting virtual machines on sites that are configured for Storage DRS or Storage vMotion if you follow certain guidelines.
The behavior of Storage DRS or Storage vMotion depends on whether you use Site Recovery Manager with array-based replication or with vSphere Replication.
For information about how Site Recovery Manager handles datastore tagging for Storage DRS, see http://kb.vmware.com/kb/2108196.