You might come across some limitations while working with AppStacks.
Support for physical endpoints and AppStacks is only given under the following constraints:
VHD In-Guest mode is the only supported machine manager mode
Constant network connection is required
OS on the physical device should be non-persistent, streamed, or both
Provisioning of Internet Explorer into an AppStack is not supported. Due to the tight OS integration and dependencies, use an application isolation technology such as VMware ThinApp. VMware App Volumes can then be utilized for delivery of the isolated application package.