When an App Volumes agent make an HTTP request to the App Volumes Manager, NTLM is used to authenticate the user and user account with the entry in the Active Directory.
You can disable NTLM by defining a system environment variable on the machine where App Volumes Manager is installed.
See https://technet.microsoft.com/en-us/library/jj852241(v=ws.11).aspx to understand the implications of disabling NTLM.