If you do not want a registry rule to be effective anymore, you can either disable it, which leaves it in the registry rules table, or delete it from the table. In either case, the rule stops affecting newly discovered files.
However, files that were affected by the rule before it was disabled retain any file state assigned to them by the rule.
If you think you might use the rule again, disabling it temporarily is the best choice.
Disable a Registry Rule
While on the Registry tab, click the View Details icon next to the rule you want to disable, and select the Disabled radio button. Saving your changes disables the rule.
Delete a Registry Rule
While on the Registry tab, click the delete icon X next to the rule you want to delete, and select OK on the confirmation page.
Deleting a rule eliminates it permanently – there is no undo or retrieval for a deleted rule. Because of that, be sure you actually want to delete the rule.