VMware vSAN might have different performance characterizations compared to your on-premises storage solution. Comprehensive performance baseline (including per virtual disk throughput, IOPS, latency) should be collected and compared to performance characterizations of the hybrid cloud platform. Ensure that the target cluster in VMware Cloud on AWS can sustain required IOPS and provides required throughput.
While sizing a VMware Cloud on AWS to host enterprise application workload ensure to take into account not only capacity, but performance requirements, while each host contributes to a single vSAN datastore.
Choosing a RAID level not only influences capacity capabilities, but also has a performance impact. For enterprise applications with high performance requirements an SPBM with RAID 1 will have a positive performance impact.