When Horizon Persona Management is enabled, you cannot manage Horizon users' personas by using the Windows roaming profiles functions.

For example, if you log in to a desktop's guest operating system, navigate to the Advanced tab in the System Properties dialog box, and change the User Profiles settings from Roaming profile to Local profile, Horizon Persona Management continues to synchronize the user's persona between the local desktop and the remote persona repository.

However, you can specify files and folders within users' personas that are managed by Windows roaming profiles functionality instead of Horizon Persona Management. You use the Windows Roaming Profiles Synchronization policy to specify these files and folders.