When a remote desktop window is open, you can use the Window > Enter Full Screen menu item or the expander arrows in the upper-right corner of the remote desktop window to extend the remote desktop across multiple monitors. You can select the Window > Use Single Display in Full Screen menu item to make the remote desktop fill only one monitor.

The monitors do not have to be in the same mode. For example, if you are using a laptop that is connected to an external monitor, the external monitor can be in portrait mode or landscape mode.

You can select a full-screen option from the Settings dialog box after you connect to a server and before you open a remote desktop. Click the Settings button (gear icon) in the upper-right corner of the desktop and application selection window, select the remote desktop, and select a full-screen option from the Full Screen drop-down menu.

You can use the selective multiple-monitor feature to display a remote desktop window on a subset of your monitors. For more information, see Select Specific Monitors in a Multiple-Monitor Setup.