An end user can run Skype for Business inside a virtual desktop without negatively affecting the virtual infrastructure and overloading the network. During Skype audio and video calls, all media processing takes place on the client machine instead of in the virtual desktop.
To use this feature, you must install the Virtualization Pack for Skype for Business feature on the client machine when Horizon Client for Windows is installed. For information, see Installing and Upgrading Horizon Client for Windows.
An administrator must also install the VMware Virtualization Pack for Skype for Business feature on the virtual desktop when Horizon Agent is installed. For information about installing Horizon Agent, see the Windows Desktops and Applications in Horizon document.
For complete requirements, see "Configure Skype for Business" in the Horizon Remote Desktop Features and GPOs document.