Generally speaking, the URL content redirection feature supports redirection from a remote desktop or application to a client, and from a client to a remote desktop or application.

Redirection from a remote desktop or application to a client is called agent-to-client redirection. Redirection from a client to a remote desktop or application is called client-to-agent redirection.

Agent-to-client redirection
With agent-to-client redirection, Horizon Agent sends the URL to Horizon Client, which opens the default application for the protocol in the URL on the client machine. For details about configuring agent-to-client redirection, see #GUID-A3CA2652-F613-4B17-9B57-66E09F4BE097.
Client-to-agent redirection
With client-to-agent redirection, the system opens a remote desktop or remote application that you specified to handle the URL. For details about configuring client-to-agent redirection, see #GUID-AFC211BC-2E5F-4F0F-9ACF-01FA53124F54 .

You can redirect some URLs from a remote desktop or application to a client, and redirect other URLs from a client to a remote desktop or application. You can redirect any number of protocols, including HTTP, HTTPS, mailto, and callto.