You can use VMware vSAN storage with VMware Live Site Recovery and vSphere Replication.

VMware Live Site Recovery supports vSphere Replication with vSAN and vSAN Express Storage. You cannot use vSAN storage with array-based replication.

For information about the compatible versions of vSphere Replication and vSAN, see VMware Product Interoperability Matrix at https://interopmatrix.vmware.com/Interoperability.

For information about using vSphere Replication with vSAN, see Using vSphere Replication with VMware vSAN Storage in vSphere Replication Administration.