Special considerations must be made on multi-socket systems. With the proper configuration, NSX ensures (through the converged VDS) that the traffic is NUMA aligned for physical NICs, EDP lcores, and VMs.
The following figure demonstrates the best practices for NUMA node design on a dual socket system. To perform NUMA alignment on the vSwitching layer, at least two physical NICs are required. One NIC must be installed in a PCI slot that aligns to socket 0 (NUMA Node 0), and the other must be installed in a PCI slot that aligns to socket 1 (NUMA Node 1). This ensures that the traffic is NUMA aligned, thereby maximizing throughput and lowering jitter.