The cluster design must consider the workloads that the cluster handles. Different cluster types in this design have different characteristics.
When you design the cluster layout in vSphere, consider the following guidelines:
Use fewer, larger ESXi hosts, or more, smaller ESXi hosts.
A scale-up cluster has fewer, larger ESXi hosts.
A scale-out cluster has more, smaller ESXi hosts.
Compare the capital costs of purchasing fewer, larger ESXi hosts with the costs of purchasing more, smaller ESXi hosts. Costs vary between vendors and models.
Evaluate the operational costs for managing a few ESXi hosts with the costs of managing more ESXi hosts.
Consider the purpose of the cluster.
Consider the total number of ESXi hosts and cluster limits.