You can remove a USB controller from a virtual machine if you do not want to connect to USB devices.
Verify that all USB devices are disconnected from the virtual machine.
- In the vSphere Client inventory, right-click the virtual machine and select Edit Settings.
- Click the Hardware tab and select USB controller.
- Click Remove.
- Click OK to save your changes.
The controller is no longer connected to the virtual machine, but remains available to add at a later time.