In most network deployments, generated MAC addresses are a good approach. However, you might need to set a static MAC address for a virtual machine adapter with unique value.
The following cases show when you might set a static MAC address:
Virtual machine adapters on different physical hosts share the same subnet and are assigned the same MAC address, causing a conflict.
Ensure that a virtual machine adapter always has the same MAC address.
By default, VMware uses the Organizationally Unique Identifier (OUI)
00:50:56 for manually generated addresses, but all unique manually generated addresses are supported.
Make sure that no other non-VMware devices use addresses assigned to VMware components. For example, you might have physical servers in the same subnet, which use
22:22:22:22:22:22 as static MAC addresses. The physical servers do not belong to the vCenter Server inventory, and vCenter Server is not able to check for address collision.