After you have performed configuration or testing steps required by the wake protocol you are using on each host, you can enable vSphere DPM.
Configure the power management automation level, threshold, and host-level overrides. These settings are configured under Power Management in the cluster’s Settings dialog box.
You can also create scheduled tasks to enable and disable DPM for a cluster using the Schedule Task: Change Cluster Power Settings wizard.
If a host in your DRS cluster has USB devices connected, disable DPM for that host. Otherwise, DPM might turn off the host and sever the connection between the device and the virtual machine that was using it.