Memory reliability, also known as error isolation, allows ESXi to stop using parts of memory when it determines that a failure might occur, as well as when a failure did occur.
When enough corrected errors are reported at a particular address, ESXi stops using this address to prevent the corrected error from becoming an uncorrected error.
Memory reliability provides better VMkernel reliability despite corrected and uncorrected errors in RAM. It also enables the system to avoid using memory pages that might contain errors.