You can run host management commands such as ESXCLI commands, vicfg- commands, and other commands with several different connection options.
You can target hosts directly or target a vCenter Server system and specify the host you want to manage. If you are targeting a vCenter Server system, specify the Platform Services Controller, which includes the vCenter Single Sign-On service, for best security.
Important: For connections to
ESXi hosts version 6.0 or later, vCLI supports both the IPv4 protocol and the IPv6 protocol. For earlier versions, vCLI supports only IPv4. In all cases, you can configure IPv6 on the target host with several of the networking commands.
See the Getting Started with vSphere Command-Line Interfaces documentation for a complete list and examples.