You can modify ESXi configuration files in the ESXi Configuration Store (ConfigStore) by using the /bin/configstorecli tool.

The goal of the ESXi Shell tool configstorecli, introduced in ESXi 7.0 Update 1, is to manage all configurations for an ESXi host centrally, instead of using different methods and a variety of configuration files.

For more information on how to manage ConfigStore, see VMware knowledge base articles 82227 and 93720.