A host that is enabled for hyperthreading should behave similarly to a host without hyperthreading. You might need to consider certain factors if you enable hyperthreading, however.

ESXi hosts manage processor time intelligently to guarantee that load is spread smoothly across processor cores in the system. Logical processors on the same core have consecutive CPU numbers, so that CPUs 0 and 1 are on the first core together, CPUs 2 and 3 are on the second core, and so on. Virtual machines are preferentially scheduled on two different cores rather than on two logical processors on the same core.

If there is no work for a logical processor, it is put into a halted state, which frees its execution resources and allows the virtual machine running on the other logical processor on the same core to use the full execution resources of the core. The VMware scheduler properly accounts for this halt time, and charges a virtual machine running with the full resources of a core more than a virtual machine running on a half core. This approach to processor management ensures that the server does not violate any of the standard ESXi resource allocation rules.

Consider your resource management needs before you enable CPU affinity on hosts using hyperthreading. For example, if you bind a high priority virtual machine to CPU 0 and another high priority virtual machine to CPU 1, the two virtual machines have to share the same physical core. In this case, it can be impossible to meet the resource demands of these virtual machines. Ensure that any custom affinity settings make sense for a hyperthreaded system.