You can access vSphere components through the vSphere Client, the VMware Host Client, and the vSphere Command-Line Interface.

vSphere Client
The vSphere Client, introduced in vSphere 6.5, is an HTML5-based client and is included with vCenter Server. As of vSphere 7.0, the vSphere Web Client has been deprecated. The vSphere Client is the primary interface for connecting to and managing vCenter Server instances.
VMware Host Client

The VMware Host Client is a Web-based application that you can use to manage individual ESXi hosts that are not connected to a vCenter Server system.

For more information about the VMware Host Client, see vSphere Single Host Management - VMware Host Client.

vSphere Command-Line Interfaces
vSphere supports multiple command-line interfaces for configuring virtual machines, ESXi hosts, and vCenter Server.