vSAN 6.2 and later supports IPv6.
vSAN supports the following IP versions.
IPv6 (vSAN 6.2 and later)
Mixed IPv4/IPv6 (vSAN 6.2 and later)
In releases earlier than vSAN 6.2, only IPv4 is supported. Use mixed mode when migrating your vSAN cluster from IPv4 to IPv6.
IPv6 multicast is also supported. However, some restrictions are applicable with IPv6 and IGMP snooping on Cisco ACI. For this reason, do not implement IPv6 for vSAN using Cisco ACI.
For more information about using IPv6, consult with your network vendor.