The raw RPC interface varies for one of the three OS types available.

Linux:       vmtoolsd --cmd="guestlib.stat.get <encoding> <stat>"
Mac:         vmtoolsd --cmd="guestlib.stat.get <encoding> <stat>"
Windows:     vmtoolsd.exe --cmd="guestlib.stat.get <encoding> <stat>"

This is a raw form of the statistics API. Function calls or CLI are preferred.