ESXi supports iSCSI storage and up to 5 node WSFC clusters.

  • ESXi supports iSCSI for Windows Server 2012 and above releases. Windows Server 2008 SP2 and earlier are not supported.
  • Cluster-across-box (CAB) and cluster-in-a-box (CIB) are supported. A mixture of CAB and CIB is not supported.
  • Clustered VMDKs on VMFS datastore in CAB are not supported over iSCSI.
  • No qualification is needed for software iSCSI initiator in a guest operating system.
  • N+1 cluster configuration comprising of a cluster between "N" virtual machines on separate ESXi hosts and one physical machine running Windows natively is supported.
  • All hosts must be running ESXi 6.0 or later.
  • Cluster nodes registered to hosts with different ESXi versions are not supported.
  • Mixed mode of iSCSI config is supported.