The best practices for load balancers are detailed here.
Review the latest API updates to use for node status
Starting with vRealize Operations 8.0, the node status API has been updated to use an optional set of services to get the aggregated statuses of the node. See vRealize Operations Manager Load Balancing for the latest information.
Use load balancers to provide a single UI entry for users
Use of a load balancer to provide multiple users a single URL for accessing the vRealize Operations cluster alleviates the need for users to remember logging into separate node names and accessing specific nodes.
Use load balancers to provide high availability for remote collectors with End Point Operations agents
Use a load balance to group multiple remote collectors when using End Point Operations agents to provide high availability and redundancy.