You can configure and run NSX-T on a vSphere Distributed Switch (VDS) switch.

In NSX-T 3.0, a host transport node can be prepared by installing NSX-T on a VDS switch. To prepare an an NSX Edge VM as a transport node, you can only use an N-VDS switch. But, you can connect an NSX Edge VM to any of the supported switches (VSS, VDS, or N-VDS) depending on the topology in your network.

After you prepare a cluster of transport node hosts with VDS as the host switch, you can do the following:
  • Manage NSX-T transport nodes on a VDS switch.
  • Realize a segment created in NSX-T as an NSX Distributed Virtual port group in vCenter Server.
  • Migrate VMs between vSphere Distributed Virtual port groups and NSX Distributed Virtual port groups.
  • Send VMs traffic running on both these type of port groups.