To remove all process monitoring configuration from multiple hosts and the corresponding application instances from the topology:
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Open the Domain Manager Administration Console, right-click your ESM server (INCHARGE-ESM by default), and select Configure ESM Process Monitoring. Configure ESM Process Monitoring.
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In the Configure ESM Process Monitoring window, specify the search criteria and click Find to list the hosts.
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Select one or more hosts and click Unconfigure.
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Click Yes to confirm the removal of the process monitoring configuration from the selected hosts. This also removes the application instances from the topology.