You can manage uplink adapters, which represent the physical NICs that connect the ESXi host to the network by using the esxcli network nic or the vicfg-nics command. You can also use esxcli network vswitch and esxcfg-vswitch to link and unlink the uplink.
You can use vicfg-nics to list information and to specify speed and duplex setting for the uplink.
You can use esxcli network nic to list all uplinks, to list information, to set attributes, and to bring a specified uplink down or up.