You can temporarily disable a path with ESXCLI for maintenance or other reasons, and enable the path when you need it again.
If you are changing a path's state, the change operation fails if I/O is active when the path setting is changed. Reissue the command. You must issue at least one I/O operation before the change takes effect.
Specify one of the options listed in Connection Options for vCLI Host Management Commands in place of <conn_options>
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Procedure
What to do next
When you are ready, set the path state to active again.
esxcli <conn_options> storage core path set --state active --path vmhba32:C0:T1:L0